DERIVATIVES OF ALKYLBENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 1999 - IPC

Abstract RU 2142940 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of alkylbenzoylguanidines of the formula (I) where values A, R¹,R² and R³ are given in the invention claim. New compounds and their physiologically compatible salts show an active effect against arrhythmia and properties of inhibitors of Na⁺/H⁺-antiporter. Invention describes also a method of their synthesis and a pharmaceutical composition based on thereof. EFFECT: improved method of synthesis, valuable pharmacological properties of compounds. 5 cl, 1 tbl, 17 ex

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RU 2 142 940 C1

Authors

Rol'F Gerike

Diter Dorsh

Manfred Baumgart

Klaus-Otto Mink

Norbert Bajer

Dates

1999-12-20—Published

1995-08-30—Filed