FIELD: medicine. SUBSTANCE: described are new 4-sulfonyl-or sulfinyl benzoyl guanidine of formula I: 
wherein R6 is alkyl having 1-4 carbon atoms of phenyl, n is 1 or 2 or physiologically tolerable salts thereof. Said compounds show antiarrhythmic properties and act as inhibitors of cellular Na/H anticarrier. Also described are method of preparation of said compounds and composition based thereon. EFFECT: improved properties of the title compounds. 5 cl, 1 dwg, 18 ex, 1 tbl
| Title |
Year |
Author |
Number |
| DERIVATIVES OF 4-MERCAPTOBENZOYLGUANIDINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1996 |
- Rol'F Gerike
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2162079C2 |
| FLUORINE-CONTAINING BENZOYL GUANIDINES, METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF PREPARATION THEREOF |
1996 |
- Diter Dorsh
- Manfred Baumgart
- Rol'F Gerike
- Klaus-Otto Mink
- Norbert Bajer
|
RU2159230C2 |
| HETEROCYCLYL-BENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
1995 |
- Gerike Rol'F
- Dorsh Diter
- Baumgart Manfred
- Mink Klaus-Otto
- Bajer Norbert
|
RU2152390C1 |
| 4-AMINOBENZOYL GUANIDINES, METHODS OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITING CELLULAR Na/H-ANTIPORTER |
1996 |
- Rol'F Gerike
- Manfred Baumgart
- Norbert Bajer
- Klaus-Otto Mink
|
RU2160728C2 |
| HETEROCYCLYLOXY BENZOYL GUANIDINES, METHODS OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARATION THEREOF |
1995 |
- Rol'F Gerike
- Diter Dorsh
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2160732C2 |
| DERIVATIVES OF ALKENYLBENZOYLGUANIDINE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
1996 |
- Rol'F Gerike
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2172733C2 |
| ARYLBENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
1995 |
- Rol'F Gerike
- Diter Dorsh
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2153490C2 |
| DERIVATIVES OF BENZOYLGUANIDINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF ITS PREPARING |
1995 |
- Rol'F Gerike
- Diter Dorsh
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2158255C2 |
| ORTHO-SUBSTITUTED DERIVATIVES OF BENZOIC ACID, METHOD OF THEIR SYNTHESIS, METHOD OF PREPARING PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL COMPOSITION |
1995 |
- Rol'F Gerike
- Diter Dorsh
- Manfred Baumgart
- Klaus-Otto Mink
- Norbert Bajer
|
RU2125981C1 |
| 4-AMINO-1-PIPERIDYLBENZOYLGUANIDINES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
1995 |
- Rol'F Gerike
- Manfred Baumgart
- Diter Dorsh
- Norbert Bajer
- Klaus-Otto Mink
- Ingeborg Lues
|
RU2140412C1 |
