FIELD: medicine. SUBSTANCE: microsphere has gelatinized polar nucleus coated with n lipid double layers concentrically applied in alternating manner or n aqueous layers in liquid state and n gelatinized polar layers. n is an integer number being equal to or greater than 1. The layers are produced by delipidation of liposomes called liposomes with gelatinized polar nucleus having at least one external lipid layer and at least one internal aqueous polar phase containing gelatinized substance. The method involves producing microspheres with controlled diameter. EFFECT: wide range of applications as active substance carrier or diagnostic agent; high stability. 12 cl, 6 dwg, 2 tbl
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Authors
Dates
2000-08-20—Published
1995-04-12—Filed