FIELD: medicine.
SUBSTANCE: invention can be used for genomic changes detection in cell lines of mammals, occurring within cell cultures passages number expansion, necessary for augmentation of materials for medical purposes. Test-system is based on RAPD-PCR analysis of RNA. Method was used for control of human tissue stromal cells and human fibroblast cultures of different cultivation continuance.
EFFECT: invention allows highly sensible control of genome's stability in cell cultures of different cultivation continuance.
4 cl, 6 dwg, 1 tbl, 2 ex
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Authors
Dates
2010-06-20—Published
2008-04-16—Filed