FIELD: medicine.
SUBSTANCE: invention refers to biotechnology, and can be used for creation of vaccine preparations for colibacillosis in animals. A method for producing colibacillosis anatoxin provides sampling of epizootic Escherichia coli strains able to produce a thermolabile, thermostable and shiga like toxin, separate cultivation on a nutritious broth for 6-7 days, culture inactivation by adding formalin to the concentration 0.3-0.4 % at temperature 37°C for 14 days and mixing in equal volumes, and separation of a bacterial mass by means of sterilisation filtration.
EFFECT: invention provides more efficient prevention of colibacillosis in animals.
1 tbl, 1 ex
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Authors
Dates
2011-10-27—Published
2010-07-27—Filed