METHOD FOR PREVENTING ESCHERICHIOSIS IN CALVES Russian patent published in 2022 - IPC A61K39/108 A61K31/739 A61K31/78 A01K67/00 

FIELD: veterinary medicine.

SUBSTANCE: invention relates to the field of veterinary medicine, pertains to a method for preventing escherichiosis in calves. The method for preventing escherichiosis includes double immunisation of pregnant cows with an anatoxin vaccine against escherichiosis at an interval of 15 days and double introduction of the preparation to calves born from the immunised pregnant cows. The pregnant cows and calves born therefrom are therein immunised with an anatoxin vaccine containing a pyrogenal solution containing 100 mcg of the active substance, and a 3% aqueous solution of polyacrylic acid, as adjuvants, introduced consecutively, followed by mixing, into an acellular culture medium containing thermolabile, thermostable and shiga-like Escherichia coli toxins inactivated by formalin until the final concentration thereof of 0.4%, with the following component ratio, % wt.: pyrogenal solution containing 100 mcg of the active substance 9 to 11; 3% aqueous solution of polyacrylic acid 9 to 11; acellular culture medium containing inactivated thermolabile, thermostable and shiga-like Escherichia coli toxins up to 100. Pregnant cows are therein immunised for the first time 30 days, the second time 15 days prior to calving at a dose of 5 and 10 ml, respectively, and calves are vaccinated twice, for the first time at the age of 15 to 20 days, the second time after 10 to 14 days at a dose of 1 and 2 ml, respectively.

EFFECT: possibility of preventing escherichiosis in calves.

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