Show metadata Hide metadata

(19)

(11)

2 455 280

(13)

(51)

IPC

C07C231/06(2006-01-01)

C07C233/06(2006-01-01)

(21) (22)

Application

2011101002/04, 2011-01-12

(24)

Start date

2011-01-12

(22)

Actual filing date

2011-01-12

(45)

Published

2012-07-10

(72)

Inventor

Dzhemilev Usein MemetovichKhusnutdinov Ravil IsmagilovichShchadneva Nina AlekseevnaMajakova Julija Jur'EvnaOshnjakova Tat'Jana Mikhajlovna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Nauk Institut Neftekhimii I Kataliza Ran

METHOD OF PRODUCING N-(1-ADAMANTYL)ACETAMIDE Russian patent published in 2012 - IPC C07C231/06 C07C233/06

Abstract RU 2455280 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically to a novel method of producing N-(1-adamantyl)acetamide, used to produce pharmaceutical preparations, involving reaction of 1-chloroadamantane with acetonitrile in the presence of water under the action of manganese-containing catalysts such as MnC₂, MnBr₂, Mn(acac)₂, Mn₂(CO)₁₀ at temperature 130°C for 2-3 hours, with molar ratio of reactants [Ad-Cl]:[CH₃CN]:[H₂O]:[Mn]=100:300-400:100:3.

EFFECT: ensuring complete conversion of 1-bromoadamantane and absence of by-products, ie, the only product is N-(1-adamantyl)acetamide.

1 cl, 8 ex, 1 tbl

Similar patents RU2455280C1

Title	Year	Author	Number
METHOD OF PRODUCING N-(1-ADAMANTYL)ACETAMIDE	2014	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Khisamova Lilija Fagimovna	RU2576312C1
METHOD OF PRODUCING N-(1-ADAMANTYL)ACETAMIDE	2010	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Khisamova Lilija Fagimovna	RU2443680C2
N-(1-ADAMANTYL)ACETAMIDE SYNTHESIS METHOD	2008	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Mukhametshina Lilija Fagimovna	RU2401828C2
METHOD OF OBTAINING 1-ACETAMIDO-3,5-DIMETHYLADAMANTANE	2014	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Khisamova Lilija Fagimovna Kislitsina Ksenija Sergeevna	RU2574077C1
METHOD OF PRODUCING N-(1-ADAMANTYL)ACETAMIDE	2010	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Khisamova Lilija Fagimovna	RU2448953C2
METHOD FOR OBTAINING 1-FORMAMIDOADAMANTANE	2014	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Khisamova Lilija Fagimovna	RU2575213C1
METHOD OF PRODUCING 1-ACETYLADAMANTANE	2008	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Mukhametshina Lilija Fagimovna	RU2440326C2
METHOD OF PRODUCING (1-ADAMANTYL)ACETONE (2-OXOPROPYLADAMANTANE)	2012	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Kislitsina Ksenija Sergeevna Veklov Vitalij Aleksandrovich Borisova Ksenija Olegovna	RU2504535C2
METHOD FOR PRODUCING N-(ADAMANTANE-1-YL)AMIDES	2017	Khusnutdinov Ravil Ismagilovich Bajguzina Alfiya Ruslanovna Lutfullina Alsu Rafaelovna	RU2679607C1
METHOD OF PRODUCING 1,3-DICHLOROADAMANTANE	2011	Dzhemilev Usein Memetovich Khusnutdinov Ravil Ismagilovich Shchadneva Nina Alekseevna Oshnjakova Tat'Jana Mikhajlovna	RU2459797C1

RU 2 455 280 C1

Authors

Dzhemilev Usein Memetovich

Khusnutdinov Ravil Ismagilovich

Shchadneva Nina Alekseevna

Majakova Julija Jur'Evna

Oshnjakova Tat'Jana Mikhajlovna

Dates

2012-07-10—Published

2011-01-12—Filed