METHOD OF PRODUCING ADAMANTYL-CONTAINING PHENOL HALIDE DERIVATIVES Russian patent published in 2012 - IPC C07C39/367 C07C37/11 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing diadamantyl-containing derivatives of 4-phenol halides of general formula , where R₁=R₃=Ad, R₂=Br (I); R₁=R₃=Ad, R₂=Cl (II); R₁=R₃=Ad, R₂=F (III), which can be used as intermediate products for synthesis of biologically active substances, antioxidants and antipolymerisation agents. The method involves reaction of an adamantane derivative with phenol in molar ratio of (2.05-2.15):1, at temperature 200-220°C for 12-18 hours. The adamantane derivative used is a mixture of 1-adamantanol and 1-bromadamantane in molar ratio 1:0.05-0.15, and the phenol used phenol halide selected from 4-bromophenol, 4-chlorophenol, 4-fluorophenol.

EFFECT: invention enables to obtain end products using a simple and environmentally friendly method.

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