CONJUGATE FOR PHOTODYNAMIC DIAGNOSTICS OR THERAPY AND METHOD OF OBTAINING THEREOF Russian patent published in 2014 - IPC A61K31/695 A61K31/315 A61K31/702 A61K49/06 A61K49/10 A61K49/12 A61P35/00 C09B47/04

Abstract RU 2537228 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to conjugate for photodynamic diagnostics or therapy of cancer, to method of obtaining conjugate and to conjugate-containing composition, intended for diagnostics or therapy of cancer. Conjugate in form of nanoparticles with size 100-250 nm represents acetylated biologically compatible polysaccharide - chondroitin sulfate, bound by means of ester bond with phthalocyanine-based compound of formula . Conjugate is obtained by acetyation of chondroitin sulfate, dissolution of chondroitin sulfate in organic solvent and addition of phthalocyanine-based compound of said formula and catalyst to chondroitin sulfate.

EFFECT: obtained is conjugate for photodynamic diagnostics or therapy of cancer.

7 cl, 16 dwg, 2 ex

Similar patents RU2537228C1

Title	Year	Author	Number
COVALENT CONJUGATES BASED ON PHTHALOCYANINES AND METHYLPHEOPHORBIDE A, METHODS FOR PREPARE AND USE THEREOF IN MEDICINE	2019	Tomilova Larisa Godvigovna Pushkarev Viktor Evgenevich Balashova Irina Olegovna Shestov Vladimir Ilich Ponomarev Gelij Vasilevich Kojfman Oskar Iosifovich Platonova Yana Borisovna Volov Aleksandr Nikolaevich	RU2722309C1
?-FORM ZINC-PHTHALOCYANINE NANOWIRES HAVING ENHANCED WATER SOLUBILITY AND WATER DISPERSIBILITY, COMPOSITE OF AN ?-FORM ZINC- PHTHALOCYANINE NANOWIRE/PHENOTHIAZINE, AND METHOD FOR PREPARING THEREOF	2012	Choj Khi Cheul Mun Khaj Ken Li San Kho	RU2602698C2
PHOTOSENSITIZE BASED ON CARBOCYANINE DYE FOR PHOTODYNAMIC THERAPY OF TUMOURS	2016	Pozdnyakova Natalya Vladimirovna Shevelev Aleksej Borisovich Radchenko Aleksandra Shamilevna Kuzmin Vladimir Aleksandrovich Nekipelova Tatyana Dmitrievna Borisevich Yurij Evgenevich Kostyukov Aleksej Aleksandrovich Golovina Galina Vladimirovna Zylkova Marina Valerevna Biryukova Yuliya Konstantinovna	RU2638131C1
METAL-GLYCOPROTEIN COMPLEXES AND USE THEREOF AS CHEMOTHERAPEUTIC COMPOUNDS	2016	Mendel Arkadij	RU2742981C2
TETRAAZACHLORINES AS PHOTOSENSIBILIZATORS FOR PHOTODYNAMIC THERAPY	2004	Barkanova Svetlana Vasil'Evna Bystritskij Georgij Iosifovich Vorozhtsov Georgij Nikolaevich Karmakova Tat'Jana Anatol'Evna Luzhkov Jurij Mikhajlovich Luk'Janets Evgenij Antonovich Makarova Elena Aleksandrovna Morozova Natal'Ja Borisovna Umnova Ljubov' Vasil'Evna Jakubovskaja Raisa Ivanovna	RU2278119C1
NANOCOMPOSITE PHOTOSENSITISER FOR METHOD OF PHOTODYNAMIC CELL EFFECT	2006	Gurtov Valerij Alekseevich Kuznetsov Sergej Nikolaevich Pikulev Vitalij Borisovich Saren Andrej Aleksandrovich	RU2329061C1
PHOTODYNAMIC THERAPY KIT	2019	Sokolov Pavel Mikhajlovich Nabiev Igor Rufailovich Nifontova Galina Olegovna	RU2740552C1
IMMUNOLIPOSOMAL FORM OF PHOTOSENSITISER	2009	Baryshnikov Anatolij Jur'Evich Volkov Nikolaj Nikolaevich Ivanov Andrej Valentinovich Ivanov Pavel Konstantinovich Ignat'Eva Elena Vladimirovna Kortava Marta Anatol'Evna Meerovich Gennadij Aleksandrovich Meerovich Igor' Gennad'Evich Oborotova Natalija Aleksandrovna Polozkova Alevtina Pavlovna Orlova Ol'Ga L'Vovna Sokolova Darina Vadimovna Sokolova Zinaida Aleksandrovna Khugaeva Ol'Ga Vaznoevna	RU2410090C1
PHOTOSENSITIZING AGENTS FOR PHOTODYNAMIC THERAPY	2005	Vorozhtsov Georgij Nikolaevich Karmakova Tat'Jana Anatol'Evna Luzhkov Jurij Mikhajlovich Luk'Janets Evgenij Antonovich Morozova Natal'Ja Borisovna Negrimovskij Vladimir Mikhajlovich Pankratov Andrej Aleksandrovich Pljutinskaja Anna Dmitrievna Chissov Valerij Ivanovich Juzhakova Ol'Ga Alekseevna Jakubovskaja Raisa Ivanovna	RU2282646C1
SULFOSUBSTITUTED PHTHALOCYANINES AS PHOTOSENSITIZING AGENTS FOR PHOTODYNAMIC THERAPY	1999	Vorozhtsov G.N. Derkacheva V.M. Kazachkina N.I. Luk'Janets E.A. Feofanov A.V. Fomina G.I. Chissov V.I. Jakubovskaja R.I.	RU2183635C2

RU 2 537 228 C1

Authors

Na Kun

Li Fang Juan

Beh Beng Chan

Dates

2014-12-27—Published

2011-12-21—Filed