FIELD: medicine.
SUBSTANCE: presented group of inventions refers to medicine, molecular biology and biotechnology. A method for determining lung cancer cell sensitivity to cisplatin involving determining MLH1, ERCC1, DDB2, AKR1B1, FTL genes expression patterns vs. cisplatin IC50 for known cell lines; constructing cisplatin IC50 for these cell lines vs. derived gene expression patterns calibration straight, and hybridising on a microchip. What is also presented is a set of oligonucleotide probes presented by SEQ ID NO: 9-13.
EFFECT: presented group of inventions provides effective aids and methods for determining lung cancer cell sensitivity to cisplatin.
2 cl, 1 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
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| METHOD OF EVALUATION OF SENSITIVITY OF LUNG CANCER CELLS TO DOXORUBICIN BASED ON EXPRESSION LEVELS OF MARKER GENES AND SET FOR ITS IMPLEMENTATION | 2013 |
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