FIELD: medicine.
SUBSTANCE: method involves an immunohistological analysis of primary tumour tissue specimens aiming at determining a percentage of expression of Hsp27 non-phosphorylated molecular chaperone protein in a tumour cell nucleus with taking into account patient's menstrual health, primary tumour size and a degree of malignancy; a regression equation is calculated, and further a probability P of lymphatic cancer spread is derived. If P≥50%, a high risk is predicted, whereas P<50% shows a low risk of developing lymphatic cancer spread.
EFFECT: method enables the high-accuracy and information value prediction of developing lymphatic cancer spread accompanying invasive non-specific breast carcinoma and optimised therapeutic approach to patient management.
2 ex, 5 tbl, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREDICTING HIGH RISK OF REGIONAL METASTASIS IN BREAST CANCER | 2023 |
|
RU2816441C1 |
| METHOD FOR PREDICTION OF LYMPHATIC CANCER SPREAD ACCOMPANIED BY INVASIVE NONSPECIFIC TRIPLE-NEGATIVE BREAST CANCER | 2014 |
|
RU2558860C1 |
| METHOD FOR PREDICTION OF HAEMATOGENIC METASTASIS IN DOUBLE-SIDED SYNCHRONOUS INVASIVE NON-SPECIFIC BREAST CARCINOMA | 2015 |
|
RU2589287C1 |
| METHOD FOR PREDICTION OF HAEMATOGENOUS METASTASIS IN TRIPLE NEGATIVE INVASIVE NON-SPECIFIC BREAST CARCINOMA | 2014 |
|
RU2558863C1 |
| METHOD FOR PREDICTING LYMPHOGENOUS METASTASIS IN INVASIVE CARCINOMA OF NONSPECIFIC TYPE OF MAMMARY GLAND | 2016 |
|
RU2659938C2 |
| METHOD OF PREDICTING NODAL METASTASIS IN TWO-WAY SYNCHRONOUS INVASIVE CARCINOMA OF NON-SPECIFIC TYPE OF MAMMARY GLANDS | 2015 |
|
RU2578462C1 |
| METHOD FOR PREDICTING THE DEGREE OF RISK OF DEVELOPING HEMATOGENOUS METASTASES IN INVASIVE CARCINOMA OF A NON-SPECIFIC TYPE OF MAMMARY GLAND BASED ON THE ASSESSMENT OF THE EXPRESSION OF LIMCH1 PROTEIN | 2020 |
|
RU2755242C1 |
| METHOD FOR PREDICTION OF HAEMATOGENIC METASTASIS IN DOUBLE-SIDED METACHROMIC INVASIVE NON-SPECIFIC BREAST CARCINOMA | 2015 |
|
RU2580639C1 |
| METHOD OF PREDICTING HEMATOGENOUS METASTASIS IN INVASIVE CARCINOMA OF NONSPECIFIC TYPE OF MAMMARY GLAND BASED ON DETERMINATION OF DIFFERENT POPULATIONS OF CIRCULATING TUMOR CELLS IN BLOOD BEFORE TREATMENT | 2018 |
|
RU2678202C1 |
| METHOD FOR PREDICTION OF ANTI-OESTROGEN TAMOXIFEN THERAPY EFFECTIVENESS IN PATIENTS WITH LUMINAL BREAST CANCER | 2014 |
|
RU2558857C1 |
