FIELD: medicine.
SUBSTANCE: group of inventions discloses a method of detecting a subject with an increased content of autoantibodies to plasminogen or its fragments, a test system allowing to detect such subject, and use of the given test system for diagnostics in the subject of an oncological process. Method establishes criteria necessitating performance of a reference diagnostic examination.
EFFECT: high sensitivity of the proposed test system allows to use it as a screening test for early diagnosis of an oncological process, assessment of a risk of its development or exclusion of the diagnosis.
10 cl, 2 tbl, 2 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF DIAGNOSING ONCOLOGICAL DISEASES AND IMMUNOASSAY SET FOR ITS REALISATION | 2012 |
|
RU2522231C1 |
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|
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| RECOMBINANT POLYPEPTIDE WITH HUMAN PLASMINOGEN PROPERTIES TO CONVERT INTO PLASMIN IF ACTIVATED WHICH CATALYSES FIBRIN SPLITTING, DNA FRAGMENT CODING POLYPEPTIDE, RECOMBINANT PLASMID DNA FOR POLYPEPTIDE EXPRESSION AND TRANSFORMED Escherichia coli CELL - POLYPEPTIDE PRODUCER | 2009 |
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RU2432396C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING PLASMINOGEN, AND USE THEREOF | 2015 |
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| SYNTHETIC ANTIGEN ABILITY TO BIND β-ADRENORECEPTOR AUTOANTIBODIES | 2007 |
|
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| PROCESS FOR PREPARING FABRIC-TYPE PLASMINOGENE ACTIVATOR, STRAIN OF CULTIVATED ANIMAL CELLS, FABRIC-TYPE PLASMINOGENE ACTIVATOR CHO PRODUCER | 1987 |
|
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| HUMANIZED ANTIBODIES SPECIFIC TO ALPHA-ENOLASE AND METHODS FOR USE IN ANTITUMOR THERAPY | 2014 |
|
RU2761662C2 |
| METHOD OF IMMUNE-ENZYME ASSAY FOR DETECTING β-ADRENORECEPTOR AUTOIMMUNE ANTIBODIES IN HUMAN BLOOD PLASMA AND SERUM | 2011 |
|
RU2452964C1 |
