METHOD FOR LUNGS PROTECTION AGAINST ISCHEMIC AND REPERFUSION DAMAGE DURING CARDIAC SURGICAL INTERVENTIONS WITH ARTIFICIAL CIRCULATION Russian patent published in 2017 - IPC A61M21/00 A61H31/02 C01B21/24 

FIELD: medicine.

SUBSTANCE: artificial ventilation is performed throughout the entire period of artificial circulation with a respiratory volume of 4 ml/kg, respiration rate of 6 in 1 min, PEEP 5 cm H₂O, FiO₂ 0.3-0.4. At that, nitrogen oxide - NO is fed into the extracorporeal circulation circuit at a dose of 40 ppm immediately after the cardiopulmonary bypass is connected and the estimated volumetric rate of perfusion and perfusion balance is achieved throughout the entire period of artificial circulation. Before patient disconnection from mechanical perfusion and transferring to natural circulation, the settings of artificial ventilation are returned to the original pre-perfusion parameters, NO supply to the extracorporeal circulation circuit is stopped.

EFFECT: method allows to reduce the number of respiratory complications in the postoperative period in patients operated under IC conditions, to reduce the financial costs of treatment and to improve the results of cardiosurgical interventions.

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