FIELD: medicine.
SUBSTANCE: their preliminary visualization is performed by introduction of a complex consisting of combined photosensitizer molecules, fluorescent nanoparticles fluorescing in the infrared spectral region, and biological recognition molecules into the object under study. The complex further includes one or more plasmon nanoparticles. At that, semiconductor fluorescent nanocrystals that fluoresce in the infrared region of the spectrum are used as fluorescent nanoparticles. Irradiation of cancer cells localization is continued in the optical absorption range of fluorescent nanoparticles for detection of a fluorescent signal from fluorescent nanoparticles and subsequent induction cancer cells destruction process.
EFFECT: method provides non-invasive detection and directed destruction of cancer cells localized at great depth, with increased efficiency of visualization and destruction of cancer cells.
16 cl, 1 dwg, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PHOTODYNAMIC THERAPY KIT | 2019 |
|
RU2740552C1 |
| COMPLEX FOR THE DETECTION AND TARGETED DESTRUCTION OF CELLS | 2019 |
|
RU2743993C1 |
| CARRIER FOR DIAGNOSING, DIRECTED DELIVERY AND CONTROLLED RELEASE OF MEDICINAL AGENTS | 2018 |
|
RU2693485C1 |
| METHOD FOR BIOLOGICAL VISUALIZATION | 2016 |
|
RU2639125C1 |
| METHOD OF CREATING NANOSIZED DIAGNOSTIC LABEL BASED ON CONJUGATES OF NANOPARTICLES AND SINGLE DOMAIN ANTIBODIES | 2013 |
|
RU2560699C2 |
| METHOD FOR OBTAINING OF ANALYTICAL TEST SYSTEM BASED ON SUSPENSION MICROCHIPS FOR DISEASES MARKERS DETECTION | 2016 |
|
RU2638787C1 |
| METHOD OF SELECTIVE LASER PHOTOTHERMOLYSIS OF CANCER CELLS BY PLASMON RESONANCE NANOPARTICLES | 2015 |
|
RU2653801C1 |
| FLUORESCENT HYDROGEL FOR DETECTING BIOLOGICAL MOLECULES | 2023 |
|
RU2814452C1 |
| KIT FOR DIFFERENTIAL DIAGNOSIS OF DISEASES | 2018 |
|
RU2701742C1 |
| METHOD OF SELECTIVE DESTRUCTION OF MALIGNANT CELLS BY MAGNETIC MICROCONTAINERS WITH PHOTODYNAMIC OR PHOTOTHERMAL DYES | 2009 |
|
RU2405600C9 |
