FIELD: medicine.
SUBSTANCE: drug delivery system comprises: a medical device with a surface area, as well as a layer of drug formed on the surface area. The drug layer consists of a precipitated drug on the surface area and a carbonized or densified layer formed from the precipitated drug by irradiating the outer surface of precipitated drug. The carbonized or densified bed does not penetrate the precipitated drug substance and is capable of releasing the drug at a predetermined rate. Irradiation involves beam irradiation of accelerated neutral particles obtained from a beam of accelerated cluster gas ions. Also, method for providing a drug delivery system is disclosed.
EFFECT: improvement of the mechanism of drug release.
13 cl, 14 dwg, 1 tbl
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Authors
Dates
2018-01-29—Published
2012-08-22—Filed