FIELD: medicine.
SUBSTANCE: invention is based on free radicals generation on the surface of nanodiamonds, when they are exposed to irradiation, for example, ionizing radiation. It is possible to obtain nanodiamond complexes with a radiosensitizing agent, such as a chemical molecule or interfering RNA, aimed at the repair gene. The invention makes it possible to obtain a composition for tumour cells radiosensitizing.
EFFECT: increased efficiency of nanodiamonds.
28 cl, 18 dwg, 1 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PROTON THERAPY FOR SOLID EHRLICH CARCINOMA | 2023 |
|
RU2808984C1 |
| PHOTODYNAMIC THERAPY KIT | 2019 |
|
RU2740552C1 |
| NON-INVASIVE METHOD FOR TUMOR TISSUES GROWTH INHIBITION AND NECROSIS THEREOF | 2016 |
|
RU2665621C2 |
| METHOD OF INCREASING THE EFFICIENCY OF PROTON THERAPY ON MELANOMA STEM CELLS | 2022 |
|
RU2798733C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING DOXORUBICIN AS PART OF PHOSPHOLIPID NANOPARTICLES USING SELECTIVE DNA APTAMER MOLECULES FOR TARGETED TRANSPORT TO TUMOR CELLS | 2021 |
|
RU2794798C1 |
| METHOD FOR DIRECTED DESTRUCTION OF CANCER CELLS | 2016 |
|
RU2638446C1 |
| METHOD FOR ENHANCING TUMOR CELL DEATH IN COMBINATION OF IONIZING RADIATION AND CDK INHIBITOR | 2020 |
|
RU2777869C2 |
| METHOD FOR INCREASING THE FREQUENCY OF FORMATION OF DOUBLE-STRAND BREAKS OF DNA IN HUMAN CELLS UNDER ACTION OF IONIZING RADIATIONS UNDER CONDITIONS OF RADIO MODIFIERS | 2018 |
|
RU2699670C1 |
| RADIOPROTECTIVE, RADIOMITIGATORY AND RADIOSENSITIZING AGENT BASED ON SODIUM SALT OF AMINODIHYDROPHTHALAZINEDIONE SODIUM (DRUG TAMERON) AND OTHER ALKALI AND ALKALINE EARTH METAL SALTS OF AMINODIHYDROPHTHALAZINEDIONE | 2022 |
|
RU2804886C1 |
| NANOCOMPOSITE PHOTOSENSITISER FOR METHOD OF PHOTODYNAMIC CELL EFFECT | 2006 |
|
RU2329061C1 |
