FIELD: biotechnology.
SUBSTANCE: invention refers to biotechnology, namely to production of primary intestinal tube cells. Method involves contacting a population comprising cells of a primary intestinal tube obtained by successive differentiation of pluripotent stem cells of a human, except for a method, wherein human pluripotent stem cells are obtained by using a human embryo, with a ligand or antibody that binds a Lif receptor. Cells with which the ligand or antibody binds are selected, wherein the cells to which the ligand or antibody binds are cells of the primary intestinal tube.
EFFECT: invention widens the range of equipment.
15 cl, 13 dwg, 7 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS OF PURIFYING CELLS, DERIVED FROM PLURIPOTENT STEM CELLS | 2011 |
|
RU2607380C2 |
| METHODS OF PRODUCING CELLS OF DEFINITIVE AND PANCREATIC ENDODERM | 2013 |
|
RU2668814C2 |
| DIFFERENTIATION OF HUMAN EMBRYO STEM CELLS | 2011 |
|
RU2587634C2 |
| DIFFERENTIATION OF HUMAN EMBRYO STEM CELLS | 2011 |
|
RU2663339C1 |
| DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | 2022 |
|
RU2805433C1 |
| DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | 2018 |
|
RU2782271C2 |
| TREATMENT OF DIABETES WITH HELP OF PANCREATIC ENDOCRINE PROGENITOR CELLS | 2011 |
|
RU2682719C2 |
| USE OF EPINEPHRINE LIGANDS TO DIFFERENTIATE PANCREATIC ENDODERM CELLS | 2013 |
|
RU2650813C2 |
| METHOD FOR OBTAINING PANCREATIC ENDOCRINE CELLS (VERSIONS) AND METHOD FOR INCREASING OUTPUT OF BETA CELLS | 2013 |
|
RU2684215C2 |
| DIFFERENTIATING HUMAN EMBRYONIC STEM CELLS | 2010 |
|
RU2540021C2 |
