FIELD: biotechnology.
SUBSTANCE: method for obtaining a population of cells and an isolated crude population of cells for obtaining pancreatic endocrine cells expressing markers characteristic of the pancreatic endoderm lineage are presented. Moreover, more than 70% of cells in the population simultaneously express PDX1 and NKX6.1.
EFFECT: invention allows it to be used to stimulate the differentiation of pluripotent stem cells into insulin-producing cells.
13 cl, 2 tbl, 5 dwg, 4 ex
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