ESCHERICHIA GENUS MICROORGANISM HAVING L-TRYPTOPHAN PRODUCTIVITY, AND METHOD FOR PREPARING L-TRYPTOPHAN BY USING SAME Russian patent published in 2020 - IPC C12N15/70 C12N1/20 C12P13/22 

Abstract RU 2711981 C2

FIELD: biotechnologies.

SUBSTANCE: invention relates to biotechnology. Described is a microorganism of genus Escherichia, having improved ability to produce L-tryptophan in comparison with unmodified microorganism, where activity of phosphatase containing amino acid sequence SEQ ID NO: 1, modified with inactivation to maintain intracellular concentration of E4P (erythrosis-4-phosphate). Invention also relates to a method of producing L-tryptophan using said microorganism. In addition, the invention also relates to a method of inhibiting destruction of intracellular E4P microorganisms of genus Escherichia, involving inactivation of phosphatase activity containing amino acid sequence SEQ ID NO: 1, in microorganism of genus Escherichia.

EFFECT: invention extends the range of products for producing L-tryptophan.

4 cl, 5 tbl, 4 ex

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RU 2 711 981 C2

Authors

Park Hye Min

Lee Baek Seok

Lee Seok Myung

Kim Kyungrim

Lee Kwang Ho

Cheong Ki Yong

Lee Keun Cheol

Hong Hyeongpyo

Dates

2020-01-23Published

2016-05-10Filed