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2 824 963

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IPC

A61B17/00(2006-01-01)

G09B23/28(2006-01-01)

A61K38/22(2006-01-01)

A61K33/14(2006-01-01)

A61K9/08(2006-01-01)

A61K35/13(2015-01-01)

A61P43/00(2006-01-01)

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Application

2023129474, 2023-11-14

(24)

Start date

2023-11-14

(22)

Actual filing date

2023-11-14

(45)

Published

2024-08-16

(72)

Inventor

Kit Oleg IvanovichFrantsiiants Elena MikhailovnaKaplieva Irina ViktorovnaShikhliarova Alla IvanovnaNeskubina Irina ValerevnaVasileva Ekaterina OlegovnaTrepitaki Lidiia KonstantinovnaKachesova Polina SergeevnaPogorelova Iuliia AleksandrovnaCheriarina Natalia DmitrievnaIshonina Oksana Georgievna

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Onkologii» Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

METHOD FOR CREATING EXPERIMENTAL MODEL OF LEWIS CARCINOMA IN CONDITIONS OF HYPERTHYROIDISM Russian patent published in 2024 - IPC A61B17/00 G09B23/28 A61K38/22 A61K33/14 A61K9/08 A61K35/13 A61P43/00

Abstract RU 2824963 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental oncology, endocrinology. Preparation "Tiromel" 20 mcg/100 g in 0.5 ml of physiological saline is administered intraperitoneally to females and males of C57Bl/6 mice once day for 5 days. Then Lewis carcinoma is transplanted subcutaneously in dose of 2 million cells in 0.5 ml of normal saline.

EFFECT: method enables studying the pathogenesis of malignant growth with underlying comorbid pathology, such as hyperthyroidism, which in turn makes it possible to search for adequate effects on the tumour and to study the effect of hyperthyroidism on the development of a malignant tumour.

1 cl, 3 tbl, 2 dwg, 1 ex

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RU 2 824 963 C1

Authors

Kit Oleg Ivanovich

Frantsiiants Elena Mikhailovna

Kaplieva Irina Viktorovna

Shikhliarova Alla Ivanovna

Neskubina Irina Valerevna

Vasileva Ekaterina Olegovna

Trepitaki Lidiia Konstantinovna

Kachesova Polina Sergeevna

Pogorelova Iuliia Aleksandrovna

Cheriarina Natalia Dmitrievna

Ishonina Oksana Georgievna

Dates

2024-08-16—Published

2023-11-14—Filed