ADAM6 MICE Russian patent published in 2020 - IPC A01K67/27 C07K16/46 C12N15/85 C12N9/64

Abstract RU 2722373 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a genetically modified mouse for producing sequences of the human immunoglobulin heavy chain variable region, as well as to its cell and embryo. Also disclosed is a hybridoma for producing an antibody produced from said cell. Invention also relates to a method of providing an antibody which is specific to an antigen of interest, comprising immunising said mouse.

EFFECT: invention enables to efficiently obtain an antibody which is specific to an antigen of interest.

22 cl, 13 tbl, 11 ex, 22 dwg

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RU 2 722 373 C2

Authors

Makdonald Linn

Stivens Shon

Merfi Endryu Dzh.

Dates

2020-05-29—Published

2012-02-24—Filed