METHOD FOR SIMULATING BRAIN CONTUSION OF MILD DEGREE Russian patent published in 2020 - IPC G09B23/28 

Abstract RU 2725287 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental neurosurgery. Single impact action on an occipital area of a head of an adult rat weighing 240–300 g is carried out with a cargo of cylindrical shape from brass with weight of 200 g with a base in the form of a cone, having diameter of 2 cm, height of 1 cm, area of striker 3.14 mm2, height of load drop of 1 m, placed in guide tube, with one-stage free fall of animal from height of 30 cm into reservoir 40 × 30 × 30 cm onto the foam pad. First, the surface of the reservoir is coated with foil 0.01 mm thick, on which the middle line of the incision is applied by the blade.

EFFECT: method enables forming a cerebral injury without macroscopic foci with a corresponding microscopic and clinical picture that maximally reproduces cerebral contusion of mild degree in a human.

1 cl, 1 dwg, 1 tbl, 1 ex

Similar patents RU2725287C1

Title Year Author Number
METHOD FOR MODELING CRANIOCEREBRAL INJURY WITH PERSISTENT NEUROLOGICAL DEFICIENCY 2020
  • Vakhitov Bulat Ildarovich
  • Vakhitov Ildar Khatybovich
  • Raginov Ivan Sergeevich
  • Vakhitov Linar Ildarovich
  • Egorov Vladislav Ivanovich
  • Idiyatov Ilgiz Ilyasovich
  • Izosimova Alena Valerevna
RU2739700C1
METHOD FOR SEVERE CRANIOCEREBRAL INJURY SIMULATION 2016
  • Tikhobrazova Olga Pavlovna
  • Balyabin Aleksandr Vladimirovich
  • Mukhina Irina Vasilevna
RU2641569C1
METHOD FOR MODELING TRAUMATIC BRAIN INJURY IN RATS, USING INSTALLATION WITH SHOCK MECHANISM 2021
  • Kinzerskii Aleksandr Anatolevich
  • Shoronova Anastasiia Iurevna
  • Korzhuk Mikhail Sergeevich
  • Akulinin Viktor Aleksandrovich
  • Makareva Liubov Mikhailovna
RU2788904C1
METHOD OF TREATING CRANIOCEREBRAL INJURY AND AGENT FOR IMPLEMENTATION THEREOF 2023
  • Voevoda Mikhail Ivanovich
  • Knyazev Roman Aleksandrovich
  • Troitskij Aleksandr Vasilevich
  • Polyakov Lev Mikhajlovich
  • Lushnikova Elena Leonidovna
RU2826364C1
METHOD FOR CORRECTING NEUROLOGICAL DEFICIT IN TRAUMATIC BRAIN INJURY 2021
  • Antsiferov Oleg Vladimirovich
  • Korokin Mikhail Viktorovich
  • Gureev Vladimir Vladimirovich
  • Cherevatenko Roman Fedorovich
  • Netrebenko Aleksandr Sergeevich
  • Pokrovskij Mikhail Vladimirovich
  • Pokrovskaya Tatyana Grigorevna
  • Belyaeva Veronika Sergeevna
  • Gudyrev Oleg Sergeevich
  • Zatolokina Mariya Alekseevna
  • Pokrovskij Vladimir Mikhajlovich
  • Gureeva Anastasiya Vladimirova
  • Patrakhanov Evgenij Aleksandrovich
  • Nesterov Arkadij Vitalevich
  • Nesterova Natalya Igorevna
  • Martynova Olga Viktorovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Stepenko Yuliya Vladimirovna
  • Tsuverkalova Yuliya Mikhajlovna
RU2758245C1
METHOD FOR CORRECTING NEUROLOGICAL DEFICIENCY OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Sachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Proskurina Oksana Vladimirovna
  • Pokrovskij Vladimir Mikhajlovich
  • Patrakhanov Evgenij Aleksandrovich
  • Ekimova Natalya Viktorovna
  • Myagkaya Arina Aleksandrovna
  • Mostovykh Anna Alekseevna
RU2758433C1
METHOD FOR CORRECTION OF PATHOLOGY OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Proskurina Oksana Vladimirovna
  • Pokrovskij Vladimir Mikhajlovich
  • Patrakhanov Evgenij Aleksandrovich
  • Ekimova Natalya Viktorovna
  • Myagkaya Arina Aleksandrovna
  • Mostovykh Anna Alekseevna
RU2766785C1
METHOD FOR CORRECTING BEHAVIORAL STATUS OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Proskurina Oksana Vladimirovna
  • Martynov Mikhail Alekseevich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Duzenko Andrej Vladimirovich
  • Gubarev Artem Valerevich
  • Gasymova Sevindzh Kamranovna
  • Tikhojvanova Anna Antonovna
  • Ryabchikova Alina Alekseevna
RU2756325C1
METHOD FOR CORRECTING THE BEHAVIORAL STATUS OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN CASE OF BRAIN DAMAGE 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Proskurina Oksana Vladimirovna
  • Martynov Mikhail Alekseevich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Duzenko Andrej Vladimirovich
  • Gubarev Artem Valerevich
  • Gasymova Sevindzh Kamranovna
  • Tikhojvanova Anna Antonovna
  • Ryabchikova Alina Alekseevna
RU2763012C1
USE OF CHOLINE SALT OF SUCCINIC ACID IN PRODUCTION OF AGENTS FOR TREATING CRANIOCEREBRAL INJURY 2018
  • Pomytkin Igor Anatolevich
RU2689384C1

RU 2 725 287 C1

Authors

Radkov Ivan Valerevich

Plekhova Natalya Gennadevna

Dyujzen Inessa Valerevna

Zinovev Sergej Viktorovich

Baryshev Aleksej Nikolaevich

Dates

2020-06-30Published

2019-07-08Filed