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2 763 012

(13)

C1

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IPC

A61K31/433(2006-01-01)

A61P25/00(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2021115325, 2021-05-28

(24)

Start date

2021-05-28

(22)

Actual filing date

2021-05-28

(45)

Published

2021-12-24

(72)

Inventor

Martynova Olga ViktorovnaSkachilova Sofiya YakovlevnaCherevatenko Roman FedorovichGureev Vladimir VladimirovichAntsiferov Oleg VladimirovichPeresypkina Anna AleksandrovnaPokrovskij Mikhail VladimirovichProskurina Oksana VladimirovnaMartynov Mikhail AlekseevichSimakina Ekaterina AleksandrovnaShilova Elena VladimirovnaBelyaeva Veronika SergeevnaTsuverkalova Yuliya MikhajlovnaStepenko Yuliya VladimirovnaDuzenko Andrej VladimirovichGubarev Artem ValerevichGasymova Sevindzh KamranovnaTikhojvanova Anna AntonovnaRyabchikova Alina Alekseevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR CORRECTING THE BEHAVIORAL STATUS OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN CASE OF BRAIN DAMAGE Russian patent published in 2021 - IPC A61K31/433 A61P25/00 G09B23/28 

Abstract RU 2763012 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to experimental pharmacology. A method for correcting the behavioral status in traumatic brain injury involves modeling a traumatic brain injury in rats by free falling of a load weighing 155 grams from a height of 0.6 m. To correct the pathology, 2-amino-5-ethyl-1,3,4 -thiodiazolium-N-acetyl-aminoethanoate course of 3 days at a dose of 50 mg/kg, once, the first time - 30 minutes before the modeling of the pathology, followed by administration within 2 days.

EFFECT: invention provides an effective method for correcting the behavioral status in traumatic brain injury.

1 cl, 2 tbl, 1 ex

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RU 2 763 012 C1

Authors

Martynova Olga Viktorovna

Skachilova Sofiya Yakovlevna

Cherevatenko Roman Fedorovich

Gureev Vladimir Vladimirovich

Antsiferov Oleg Vladimirovich

Peresypkina Anna Aleksandrovna

Pokrovskij Mikhail Vladimirovich

Proskurina Oksana Vladimirovna

Martynov Mikhail Alekseevich

Simakina Ekaterina Aleksandrovna

Shilova Elena Vladimirovna

Belyaeva Veronika Sergeevna

Tsuverkalova Yuliya Mikhajlovna

Stepenko Yuliya Vladimirovna

Duzenko Andrej Vladimirovich

Gubarev Artem Valerevich

Gasymova Sevindzh Kamranovna

Tikhojvanova Anna Antonovna

Ryabchikova Alina Alekseevna

Dates

2021-12-24—Published

2021-05-28—Filed

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