Patenton — panteon of patents

(19)

RU

(11)

2 758 245

(13)

C1

(51)

IPC

G09B23/28(2006-01-01)

A61K31/495(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2021108269, 2021-03-29

(24)

Start date

2021-03-29

(22)

Actual filing date

2021-03-29

(45)

Published

2021-10-27

(72)

Inventor

Antsiferov Oleg VladimirovichKorokin Mikhail ViktorovichGureev Vladimir VladimirovichCherevatenko Roman FedorovichNetrebenko Aleksandr SergeevichPokrovskij Mikhail VladimirovichPokrovskaya Tatyana GrigorevnaBelyaeva Veronika SergeevnaGudyrev Oleg SergeevichZatolokina Mariya AlekseevnaPokrovskij Vladimir MikhajlovichGureeva Anastasiya VladimirovaPatrakhanov Evgenij AleksandrovichNesterov Arkadij VitalevichNesterova Natalya IgorevnaMartynova Olga ViktorovnaDanilenko Lyudmila MikhajlovnaTrunov Konstantin SergeevichStepenko Yuliya VladimirovnaTsuverkalova Yuliya Mikhajlovna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR CORRECTING NEUROLOGICAL DEFICIT IN TRAUMATIC BRAIN INJURY Russian patent published in 2021 - IPC G09B23/28 A61K31/495 A61P25/00 

Abstract RU 2758245 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to experimental pharmacology, and can be used to correct neurological deficits in traumatic brain injury. A method for correcting neurological deficit in traumatic brain injury involves reproducing traumatic brain injury in male rats weighing 270±20 g. To correct neurological deficit, trimetazidine is administered intragastrically at a dose of 6.6 mg/kg per day, divided into 2 doses with at intervals of 12 hours from 1 to 7 days of the experiment, inclusive. Moreover, trimetazidine begins to be administered 2 hours before the simulation of the experimental traumatic brain injury.

EFFECT: invention provides an effective method for correcting neurological deficits in an experimental model of traumatic brain injury, including the use of trimetazidine.

1 cl, 5 tbl, 1 ex

Similar patents RU2758245C1

Title Year Author Number
METHOD FOR CORRECTING NEUROLOGICAL DEFICIENCY OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Sachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Proskurina Oksana Vladimirovna
  • Pokrovskij Vladimir Mikhajlovich
  • Patrakhanov Evgenij Aleksandrovich
  • Ekimova Natalya Viktorovna
  • Myagkaya Arina Aleksandrovna
  • Mostovykh Anna Alekseevna
 RU2758433C1
METHOD FOR CORRECTION OF PATHOLOGY OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Proskurina Oksana Vladimirovna
  • Pokrovskij Vladimir Mikhajlovich
  • Patrakhanov Evgenij Aleksandrovich
  • Ekimova Natalya Viktorovna
  • Myagkaya Arina Aleksandrovna
  • Mostovykh Anna Alekseevna
 RU2766785C1
METHOD FOR CORRECTING MORPHOLOGICAL CHANGES IN TRAUMATIC BRAIN INJURY 2021
  • Antsiferov Oleg Viktorovich
  • Korokin Mikhail Viktorovich
  • Gureev Vladimir Vladimirovich
  • Cherevatenko Roman Fedorovich
  • Netrebenko Aleksandr Sergeevich
  • Pokrovskij Mikhail Vladimirovich
  • Pokrovskaya Tatyana Grigorevna
  • Belyaeva Veronika Sergeevna
  • Gudyrev Oleg Sergeevich
  • Zatolokina Mariya Alekseevna
  • Pokrovskij Vladimir Mikhajlovich
  • Gureeva Anastasiya Vladimirovna
  • Patrakhanov Evgenij Aleksandrovich
  • Nesterov Arkadij Vitalevich
  • Nesterova Natalya Igorevna
  • Martynova Olga Viktorovna
  • Danilenko Lyudmila Mikhajlovna
  • Trunov Konstantin Sergeevich
  • Stepenko Yuliya Vladimirovna
  • Tsuverkalova Yuliya Mikhajlovna
 RU2758545C1
METHOD FOR CORRECTING THE NEUROLOGICAL STATUS WITH 2-ETHYL-6-METHYL-3-HYDROXY PYRIDINIUM-N-ACETYLAMINOACETATE IN CASE OF BRAIN DAMAGE DUE TO INTRACEREBRAL HEMORRHAGE IN THE EXPERIMENT 2022
  • Shcheblykina Olesya Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Pokrovskij Mikhail Vladimirovich
  • Shcheblykin Dmitrij Valerevich
  • Kolesnichenko Pavel Dmitrievich
  • Efimenko Svetlana Vladimirovna
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Danilenko Anton Pavlovich
  • Trunov Konstantin Sergeevich
  • Danilenko Lyudmila Mikhajlovna
  • Boeva Elizaveta Valerevna
  • Cherednichenko Albina Vyacheslavovna
  • Bolgov Anton Alekseevich
 RU2786315C1
METHOD FOR CORRECTION OF CEREBRAL ISCHEMIA WITH RAPITALAM SUBSTANCE IN EXPERIMENTS 2019
  • Avdeeva Natalia Viktorovna
  • Pokrovskii Mikhail Vladimirovich
  • Korokin Mikhail Viktorovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskii Vladimir Mikhailovich
 RU2711906C1
METHOD FOR PREVENTING CEREBRAL ISCHEMIA 2018
  • Martynova Olga Viktorovna
  • Gureev Vladimir Vladimirovich
  • Pokrovskij Mikhail Vladimirovich
  • Martynov Mikhail Alekseevich
  • Beskhmelnitsyna Evgeniya Aleksandrovna
  • Kostina Darya Aleksandrovna
  • Solgalova Anastasiya Sergeevna
  • Timokhina Alena Sergeevna
  • Pokrovskaya Tatyana Grigorevna
  • Nechaeva Inna Nikolaevna
  • Korotonozhkin Aleksej Viktorovich
  • Skachilova Sofiya Yakovlevna
  • Zheltukhin Nikolaj Konstantinovich
  • Sadchikova Natalya Petrovna
 RU2696203C1
METHOD FOR PREVENTION OF BRAIN ISCHEMIA 2017
  • Martynova Olga Viktorovna
  • Pokrovskij Mikhail Vladimirovich
  • Gureev Vladimir Vladimirovich
  • Martynov Mikhail Alekseevich
  • Kostina Darya Aleksandrovna
  • Solgalova Anastasiya Sergeevna
  • Antsiferov Oleg Vladimirovich
  • Petrenko Anastasiya Aleksandrovna
  • Dovgan Anton Pavlovich
  • Shelyakina Elena Vasilevna
  • Shkileva Irina Yurevna
  • Nechaeva Inna Nikolaevna
  • Tverskoj Aleksej Vladimirovich
 RU2642961C1
METHOD FOR CORRECTING BEHAVIORAL STATUS OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN TRAUMATIC BRAIN INJURY 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Proskurina Oksana Vladimirovna
  • Martynov Mikhail Alekseevich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Duzenko Andrej Vladimirovich
  • Gubarev Artem Valerevich
  • Gasymova Sevindzh Kamranovna
  • Tikhojvanova Anna Antonovna
  • Ryabchikova Alina Alekseevna
 RU2756325C1
METHOD FOR CORRECTING THE BEHAVIORAL STATUS OF 2-AMINO-5-ETHYL-1,3,4-THIODIAZOLIUM-N-ACETYL-AMINOETHANOATE IN CASE OF BRAIN DAMAGE 2021
  • Martynova Olga Viktorovna
  • Skachilova Sofiya Yakovlevna
  • Cherevatenko Roman Fedorovich
  • Gureev Vladimir Vladimirovich
  • Antsiferov Oleg Vladimirovich
  • Peresypkina Anna Aleksandrovna
  • Pokrovskij Mikhail Vladimirovich
  • Proskurina Oksana Vladimirovna
  • Martynov Mikhail Alekseevich
  • Simakina Ekaterina Aleksandrovna
  • Shilova Elena Vladimirovna
  • Belyaeva Veronika Sergeevna
  • Tsuverkalova Yuliya Mikhajlovna
  • Stepenko Yuliya Vladimirovna
  • Duzenko Andrej Vladimirovich
  • Gubarev Artem Valerevich
  • Gasymova Sevindzh Kamranovna
  • Tikhojvanova Anna Antonovna
  • Ryabchikova Alina Alekseevna
 RU2763012C1
NEURORABILITATION AGENT BASED ON SODIUM 6-OXO-1-PHENYL-2-(PHENYLAMINO)-1,6-DIHYDROPYRIMIDINE-4-OLATE 2018
  • Sysoev Yurij Igorevich
  • Okovityj Sergej Vladimirovich
  • Anisimova Natalya Askoldovna
  • Yakovlev Igor Pavlovich
  • Chernov Nikita Maksimovich
 RU2675694C1

RU 2 758 245 C1

Authors

Antsiferov Oleg Vladimirovich

Korokin Mikhail Viktorovich

Gureev Vladimir Vladimirovich

Cherevatenko Roman Fedorovich

Netrebenko Aleksandr Sergeevich

Pokrovskij Mikhail Vladimirovich

Pokrovskaya Tatyana Grigorevna

Belyaeva Veronika Sergeevna

Gudyrev Oleg Sergeevich

Zatolokina Mariya Alekseevna

Pokrovskij Vladimir Mikhajlovich

Gureeva Anastasiya Vladimirova

Patrakhanov Evgenij Aleksandrovich

Nesterov Arkadij Vitalevich

Nesterova Natalya Igorevna

Martynova Olga Viktorovna

Danilenko Lyudmila Mikhajlovna

Trunov Konstantin Sergeevich

Stepenko Yuliya Vladimirovna

Tsuverkalova Yuliya Mikhajlovna

Dates

2021-10-27—Published

2021-03-29—Filed

download Download PDF read Similar patents