METHOD FOR PREDICTION OF THREATENING MISCARRIAGE IN AGGRAVATING CYTOMEGALOVIRUS INFECTION BY DETERMINING VASCULAR ENDOTHELIAL GROWTH FACTOR AND DOCOSAHEXAENOIC ACID IN BLOOD SERUM Russian patent published in 2020 - IPC A61B5/1477 G01N33/68 G01N33/92 

Abstract RU 2736689 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to obstetrics and pathological physiology, and can be used for prediction of risk of threatening interruption of early pregnancy accompanying exacerbation of cytomegalovirus infection. Women in blood serum are examined for VEGF-1 in ng/ml by enzyme immunoassay and docosahexaenoic acid (DHA) content in % by gas-liquid chromatography. That is followed by predicting the development of a risk of early termination of the risk of the exacerbation of cytomegaloviral infection by the prognostic index PI: PI = −62.735−0.809 × VEGF-1 + 9.845 × DHA, where PI is a discriminant function with boundary value of (−15.781). If the PI is equal to or greater than the boundary value, a risk of a threatening early miscarriage in the aggravated cytomegaloviral infection is predicted. If the PI is less than the limit value, the absence of a risk of threatening early miscarriage at the exacerbation of cytomegaloviral infection is predicted.

EFFECT: method enables higher accuracy of prediction of miscarriage in aggravated early cytomegaloviral infection by determining VEGF-1 values and docosahexaenoic acid in blood serum of pregnant women with the detected cytomegaloviral infection, prognostic index of PI, relative to which limit value of discriminant function is predicted threatening interruption of early pregnancy with exacerbation of cytomegalovirus infection.

1 cl, 2 ex

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RU 2 736 689 C1

Authors

Andrievskaia Irina Anatolevna

Ishutina Nataliia Aleksandrovna

Dates

2020-11-19Published

2020-02-21Filed