METHOD OF PREDICTING INFECTIOUS COMPLICATIONS OF CRITICAL CONDITION Russian patent published in 2021 - IPC C12Q1/6809 C12Q1/26 A61B5/145 G01N33/493 

Abstract RU 2743453 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine. The method for predicting infectious complications of critical condition is proposed. The method presupposes that one should determine the concentration of extracellular DNA in the plasma of peripheral blood during the first 24 hours after a patient is admitted to the intensive care unit. After that one should determine the intensity of exDNA oxidation in terms of the amount of oxidized deoxyguanosine (8-oxodG) in exDNA per 1 mln of nucleotides and calculate the protection index. Based on the values ​​of the protection index, infectious complications of critical condition are predicted.

EFFECT: invention provides increase in the predictive value of the concentration of extracellular DNA (exDNA) as a predictor of critical condition.

1 cl, 4 ex

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Authors

Pisarev Vladimir Mitrofanovich

Chumachenko Anastasiya Gennadevna

Filev Anton Dmitrievich

Ershova Elizaveta Sergeevna

Kostyuk Svetlana Viktorovna

Elisina Elizaveta Vladimirovna

Grigorev Evgenij Kirillovich

Dates

2021-02-18Published

2020-07-03Filed