METHOD FOR OBTAINING DIFLUOROMETHYLENE COMPOUND Russian patent published in 2021 - IPC C07C17/18 C07C22/08 

FIELD: organic synthesis.

SUBSTANCE: invention relates to a new method for producing a difluoromethylene compound (I) containing at least one -CF₂- fragment, where the method includes step A, allowing IF₅ and the disulfide compound (III) of the formula: R^A-S-S-R^A, where R^A in each case is independently an aryl, not necessarily having at least one substituent, or an alkyl, not necessarily having at least one substituent, to act on a carbonyl compound (II) containing at least one -C(O)- fragment in which the difluoromethylene compound (I) is a difluoromethylene compound, represented by the formula (1): R¹¹-CF₂-R¹² (1), in which stage A is carried out in the presence of a reaction solvent or without a reaction solvent, the reaction solvent is at least one member selected from a group consisting of aliphatic solvents, halogenated aliphatic solvents, ester solvents, nitrile solvents, aromatic solvents, simple essential solvents, N, N-dimethylformamide and dimethyl sulfoxide, The reaction temperature at stage A is from -50 to 100°С and the reaction duration at stage A1 is from 1 minute to 72 hours.

EFFECT: new method for producing difluoromethylene compound (I) is proposed, which makes it possible to avoid the formation of by-products and simplify the separation of the reaction product.

7 cl, 2 ex