METHOD FOR MULTIVARIATE PROGNOSIS OF BREAST CANCER Russian patent published in 2022 - IPC G01N33/574 A61P35/00 A61B5/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and relates to a method for multifactorial prognosis of breast cancer, during which a complex of prognostic factors is determined in tumor samples taken from patients diagnosed with breast cancer, including the expression level of proteins CK14, E-cadherin, p53, EGFR, and an assessment is made each of the prognostic factors and use the data obtained to form the prognosis of breast cancer, while the patient is additionally determined the stage of the disease, the degree of tumor differentiation, the level of expression of the FOXP3 protein, the level of expression of HER-2 receptors, the number of T-lymphocytes CD8+, the number of T-lymphocytes CD4+, each factor is assigned a number of points in accordance with the previously obtained 100-point prognostic scale, the obtained points are summed up and the total the value of points as a prognostic parameter, with a score of less than 40, the prognosis is regarded as favorable, and the prognosis is considered favorable with a survival period of patients of at least 10 years.

EFFECT: invention provides an increase in the simplicity and ease of use of the method while ensuring high objectivity and reliability of the forecast.

2 cl, 2 dwg, 1 ex