FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to a biomedical cell product with specific antitumor activity, represented by two cell populations: anti-HER2 CAR-T-NK and CAR-γδT-OIL, whose effectiveness is accompanied by simultaneous activation of innate and adoptive immune responses, intended for the treatment of patients with solid tumors expressing the epidermal growth factor receptor (HER2).
EFFECT: product obtaining from autologous mononuclear lymphocytes activated with a human recombinant cytokine preparation and subjected to genetic modification in order to express anti-HER2 CAR.
1 cl, 1 tbl, 2 ex
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