FIELD: medical diagnostics.
SUBSTANCE: invention relates to the field of medical diagnostics. Venous blood is taken, DNA is isolated from peripheral venous blood, and genetic markers of the LOXL1 gene are analyzed. A high risk of developing POAG in women is predicted when the TGG haplotype of the haploblock rs2165241, rs4886776 and rs893818 of the LOXL1 gene is detected.
EFFECT: invention provides obtaining criteria for assessing the risk of developing POAG in Russian women, natives of the Central Black Earth region of the Russian Federation, based on data on the rs2165241, rs4886776 and rs893818 polymorphic loci of the LOXL1 gene.
1 cl, 3 dwg, 4 ex
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Authors
Dates
2022-06-30—Published
2021-10-15—Filed