METHOD FOR DIAGNOSING ATOPIC DERMATITIS IN SCHOOLCHILDREN ASSOCIATED WITH THE COMPLEX EFFECTS OF TECHNOGENIC CHEMICAL COMPOUNDS: FORMALDEHYDE AND BENZO(A)PYRENE, WITH THE PRESENCE OF NEGATIVE FACTORS IN THE EDUCATIONAL ENVIRONMENT AND LIFESTYLE, AND WITH A VIOLATION OF THE NUTRITION STRUCTURE Russian patent published in 2022 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to pediatrics, immunology and dermatology. The content of formaldehyde (F) and benzo(a)pyrene (B) is determined as toxicological indicators. As laboratory indicators, the content of alpha 1-globulins, the levels of monocytes, interleukin-4 (IL-4), serum immunoglobulin A (Ig A), the relative content of CD3+CD8+-lymphocytes, and the proportion of fat mass (FM) are determined. The consumption of sausages and confectionery products by the schoolchild is established. The presence of violations of the distribution of the educational load is determined when scheduling with the establishment or absence of a light school day on Wednesday or Thursday, the time of use of technical electronic devices, as well as the frequency and frequency of physical education and sports. If F is present in the blood at the same time, it is 8.1 times higher than the regional background level, B at the level of 0.00784±0.00253 mg/dm³; with the content of alpha 1-globulins in the range of 2.8-3.2 g/dm³, the level of monocytes in the range of 6.0-9.0%, the content of IL-4 in the range of 1.02-1.99 pg/ml, the presence Serum Ig A in the range of 1.18-1.78 g/dm³, the relative content of CD3+CD8+-lymphocytes in the range of 22.2-26.4%, the content of the proportion of SM in the range of 3.10-26.0%. At the same time, the student does not have an easy school day on Wednesday or Thursday, with the duration of using the interactive whiteboard in the lesson for more than 30 minutes, with the frequency of physical education and sports less than 3 hours a week and with an increase, compared with the average daily norms, of consumption of sausages by 53% or more and 440% or more of confectionery make a conclusion that a schoolchild has atopic dermatitis.

EFFECT: method enables reliable diagnosis of atopic dermatitis in schoolchildren associated with complex exposure to technogenic chemical compounds: formaldehyde and benzo(a)pyrene, with the presence of negative factors of the educational environment and lifestyle, and with a violation of the nutrition structure.

1 cl, 3 tbl, 2 ex