A SET FOR DETERMING THE ABUNDANCE OF THE INSERTIONOF THE CONSTRUCT OF INTEREST INTO THE AAVS1LOCUS OF THE HUMAN GENOME Russian patent published in 2022 - IPC C12Q1/68 

Abstract RU 2786396 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, it can be used to determine and count the number of copies of the insertion of the structure of interest in the studied population of genetically modified cells. Disclosed is a kit for determining the abundance of insertion of the structure of interest into the AAVS1 locus of the human genome in case of a digital droplet multiplex polymerase chain reaction in real time.

EFFECT: disclosed kit provides a high-precision calculation of the abundance of the insertion of the structure of interest in the genetic material.

1 cl, 2 dwg, 1 tbl, 1 ex

Similar patents RU2786396C1

Title Year Author Number
KIT FOR DETERMINING THE ABUNDANCE OF THE APP GENE IN THE HUMAN GENOME 2021
  • Dashinimaev Erdem Bairovich
  • Artyukhov Aleksandr Sergeevich
RU2789799C1
KIT FOR DETERMINING CCR5DELTA32 MUTATIONS IN HUMAN GENOME 2020
  • Dashinimaev Erdem Bairovich
  • Artyukhov Aleksandr Sergeevich
  • Goltsova Aleksandra Sergeevna
RU2748998C1
SYSTEM FOR INCREASING EFFICIENCY OF MAMMALIAN GENOME EDITING THROUGH HOMOLOGOUS REPAIR 2022
  • Ivanenko Aleksandr Vyacheslavovich
  • Belousov Vsevolod Vadimovich
RU2808045C1
SYSTEM FOR ATTRACTING PROTEIN TO DNA BREAK SITE TO INCREASE EFFICIENCY OF MAMMALIAN GENOME EDITING 2022
  • Ivanenko Aleksandr Vyacheslavovich
  • Belousov Vsevolod Vadimovich
RU2808601C1
RIBONUCLEOPROTEIN COMPLEX FOR HUMAN GENOME EDITING BY INSERTING SEQUENCE OF INTEREST INTO IT 2020
  • Ivanenko Aleksandr Vyacheslavovich
  • Belousov Vsevolod Vadimovich
RU2750939C1
RIBONUCLEOPROTEIN COMPLEX FOR HUMAN GENOME EDITING 2020
  • Ivanenko Aleksandr Vyacheslavovich
  • Belousov Vsevolod Vadimovich
RU2749741C1
METHOD OF GENOTYPING TLR2 GENE USING RS5743708 POLYMORPHISM AND A SET OF OLIGONUCLEOTIDE PRIMERS AND PROBES FOR ITS IMPLEMENTATION 2023
  • Salamaikina Svetlana Andreevna
  • Mironov Konstantin Olegovich
  • Esman Anna Sergeevna
  • Pozdysheva Elena Alekseevna
  • Akimkin Vasilii Gennadevich
RU2805861C1
SET OF REAGENTS AND METHOD FOR DETECTING DNA OF CAUSATIVE AGENTS OF PLAGUE, ANTHRAX AND TULAREMIA BY PCR METHOD WITH HYBRIDISATION-FLUORESCENT RECORDING OF RESULTS 2013
  • Mokrievich Aleksandr Nikolaevich
  • Kudrjavtseva Tamara Jur'Evna
  • Varlamov Dmitrij Aleksandrovich
  • Sochivko Dmitrij Garrievich
  • Djatlov Ivan Alekseevich
RU2542395C1
MULTIPLEX PCR MIXTURE FOR DETERMINATION OF SEROTYPES 12FAB, 15BC, 22FA, 8 STREPTOCOCCUS PNEUMONIAE AND METHOD FOR ITS APPLICATION 2021
  • Mironov Konstantin Olegovich
  • Gaponova Irina Igorevna
  • Dunaeva Elena Alekseevna
  • Akimkin Vasilii Gennadevich
RU2787181C1
METHOD OF GENOTYPING TLR2 GENE USING RS3804100 POLYMORPHISM AND A SET OF OLIGONUCLEOTIDE PRIMERS AND PROBES FOR ITS IMPLEMENTATION 2023
  • Salamaikina Svetlana Andreevna
  • Mironov Konstantin Olegovich
  • Esman Anna Sergeevna
  • Pozdysheva Elena Alekseevna
  • Akimkin Vasilii Gennadevich
RU2805860C1

RU 2 786 396 C1

Authors

Ivanenko Aleksandr Vyacheslavovich

Belousov Vsevolod Vadimovich

Dates

2022-12-20Published

2021-12-22Filed