METHOD FOR PREDICTING AN UNFAVORABLE OUTCOME OF LOCAL AND LOCALLY ADVANCED COLON CANCER AND RECTOSIGMOID JUNCTION Russian patent published in 2023 - IPC G01N33/574 G01N33/577 

Abstract RU 2789968 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncology, and can be used to predict an unfavorable outcome of local and locally advanced colon cancer and rectosigmoid junction. Prior to surgery, the level of IL-6 and the percentage of the CD16dim56bright subpopulation of natural killers are determined in the peripheral blood. If the level of IL-6 is equal to or higher than 18.13 pg/ml, and CD16dim56bright cells are equal to or higher than 6.01% of the total number of natural killers, a high risk of an adverse outcome is predicted in the first five years after surgery.

EFFECT: method provides effective prediction of unfavorable outcome of local and locally advanced colon cancer and rectosigmoid junction by determining the level of IL-6 and the percentage of CD16dim56bright subpopulation of natural killers in the peripheral blood of a patient before surgery.

1 cl, 3 tbl, 2 ex

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RU 2 789 968 C1

Authors

Kit Oleg Ivanovich

Zlatnik Elena Iurevna

Novikova Inna Arnoldovna

Demidova Aleksandra Aleksandrovna

Kolesnikov Vladimir Evgenevich

Tolmakh Roman Evgenevich

Dates

2023-02-14Published

2022-07-05Filed