FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to oncology, and can be used to predict an unfavorable outcome of local and locally advanced colon cancer and rectosigmoid junction. Prior to surgery, the level of IL-6 and the percentage of the CD16dim56bright subpopulation of natural killers are determined in the peripheral blood. If the level of IL-6 is equal to or higher than 18.13 pg/ml, and CD16dim56bright cells are equal to or higher than 6.01% of the total number of natural killers, a high risk of an adverse outcome is predicted in the first five years after surgery.
EFFECT: method provides effective prediction of unfavorable outcome of local and locally advanced colon cancer and rectosigmoid junction by determining the level of IL-6 and the percentage of CD16dim56bright subpopulation of natural killers in the peripheral blood of a patient before surgery.
1 cl, 3 tbl, 2 ex
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Authors
Dates
2023-02-14—Published
2022-07-05—Filed