FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the use of 2-substituted 5-(hetero)alkyl-6-hydroxypyrimidine-4(1H)-ones of the general formula 
, where R=i-Pr, s-Pen, i-Pen, MeSCH2CH2, R1=SCH2CH2N(CH3)2, SCH2CH2N(CH3СH2)2, SCH2CH2N(СH2)4, SCH2CH2N(СH2)5, SCH2CH2SCH3, thiomorpholin-4-yl, or their hydrochloric acid salts as active cores of medicinal products with anxiolytic activity.
EFFECT: effective anxiolytic action.
1 cl, 2 tbl
| Title | Year | Author | Number |
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|
RU2793806C1 |
| 2-SUBSTITUTED 5-(HETERO)ALKYL-6-HYDROXYPYRIMIDINE-4(1H)-ONES HAVING ANTIDEPRESSANT ACTIVITY | 2021 |
|
RU2792888C1 |
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|
RU2744470C1 |
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|
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RU2821532C1 |
| METHOD OF PRODUCING 4-ARYL-SUBSTITUTED 7-HYDROXY-6'-PHENYL-5',6'-DIHYDRO-1'H-SPIRO[CHROMAN-2,4'-PYRIMIDINE]-2'(3'H)-ONES | 2023 |
|
RU2818006C1 |
| ANTITUBERCULOSIS AGENT BASED ON 4'-HYDROXY-1'-(2-HYDROXYPHENYL)-3'-ACYL-SPIRO[BENZO[b][1,4]THIAZINE-2,2'-PYRROLE]-3,5'(1 'H,4H)-DIONES | 2023 |
|
RU2806097C1 |
| 4'-HYDROXY-1'-(2-HYDROXYPHENYL)-3'-(4-R-BENZOYL)SPIRO[BENZO[B][1,4]THIAZINE-2,2'-PYRROLE]-3,5'( 1'H,4H)-DIONE | 2022 |
|
RU2783263C1 |
| METHOD OF PRODUCING 4-ARYL-SUBSTITUTED 8-HYDROXY-5,10A-DIMETHYL-1,3,4,10A-TETRAHYDRO-2H-CHROMENO[2,3-D]PYRIMIDIN-2-ONES(THIONS) | 2023 |
|
RU2821110C1 |
| METHOD FOR PREPARING SUBSTITUTED O-ALKYLATED HEXAHYDRO-2H-CHROMENO[4,3-D]PYRIMIDINE-2,5(1H)-DIONES | 2022 |
|
RU2796532C1 |
