FIELD: medicine; oncology; endocrinology.
SUBSTANCE: invention relates to the field of medicine, namely oncology and endocrinology, and can be used in the differential diagnosis of adrenocortical cancer (ACC) and adrenocortical adenoma (ACA) of the adrenal gland. The maximum tumor size, proliferative activity of Ki-67, the presence of nuclear polymorphism, the presence of pathological mitoses, the presence of invasion into the capsule and the presence of necrosis are determined. Based on the data obtained, the p value is calculated according to a given formula. With a p value of 0.5 or more, ACC is diagnosed, and with a p value of less than 0.5, ACA is diagnosed.
EFFECT: method allows for the differential diagnosis of ACA and ACC in patients with a tumor of the adrenal cortex of all morphological variants - classical, myxoid and oncocytic by evaluating the totality of the most significant indicators.
1 cl, 2 tbl, 4 ex
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