METHOD FOR PREDICTION OF DEVELOPING CONGENITAL CYTOMEGALOVIRUS INFECTION IN NEWBORNS Russian patent published in 2024 - IPC A61B8/08 G01N33/49 

Abstract RU 2822967 C1

FIELD: medicine.

SUBSTANCE: invention relates to infectious diseases and can be used to predict the development of congenital cytomegalovirus infection in newborns in order to prevent unfavorable outcomes. Includes assessment of: presence of acute respiratory viral infection during pregnancy, burdened obstetric-gynecological history, threatened miscarriage of present pregnancy, disturbed uterine-placental circulation, ultrasound markers of prenatal pathology, blood PCR results with detection of CMV DNA with indication of trimester of examination. Further, the obtained data are used to determine the risk of congenital infectious diseases (LDF) by formulas: LDF1 = (X1×0.64 − X2×0.2 + X3×0.84 + X4×1.53 + X5×0.69 + X6×0.14 − X7×0.92) − 1.22; LDF2 = (X1×7.68+X2×3.64 + X3×2.72 − X4×2.5 + X5×2.95 + X6×2.21 +X7×1.31) − 8.73; if LDF2 is more than LDF1, development of congenital cytomegalovirus infection in newborns is predicted.

EFFECT: method enables to reduce the examination time and increase the accuracy of early and timely prediction of the development of congenital cytomegalovirus infection in newborns in the antenatal period, and also enables the timely prescription of etiotropic therapy in the ante- and neonatal period, by assessing the most significant clinical-anamnestic, laboratory and instrumental values.

1 cl, 3 ex

Similar patents RU2822967C1

Title Year Author Number
DIAGNOSTIC TECHNIQUE FOR CONGENITAL VIRAL FOETAL DISEASE 2019
  • Vasilev Valerij Vasilevich
  • Grineva Aleksandra Aleksandrovna
  • Rogozina Natalya Vasilevna
  • Ushakova Galina Mikhajlovna
  • Ivanova Rigina Anatolevna
  • Skripchenko Natalya Viktorovna
RU2728925C1
METHOD OF PREDICTION OF PERINATAL FOETAL DEATH 2015
  • Ivanova Lidija Alekseevna
  • Shmidt Andrej Aleksandrovich
  • Grigorev Stepan Grigorevich
RU2605809C1
METHOD FOR PREDICTING PERINATAL HEPATITIS B VIRUS INFECTION IN CHILDREN 2020
  • Shilova Irina Vasilevna
  • Goryacheva Larisa Georgievna
  • Greshnyakova Vera Aleksandrovna
  • Efremova Natalya Aleksandrovna
  • Skripchenko Natalya Viktorovna
  • Grigorev Stepan Grigorevich
RU2753211C1
METHOD OF PREDICTING RETARDATION OF INTRAUTERINE DEVELOPMENT OF FETUS IN 2-D TRIMESTER IN PATIENTS WITH HIV 2010
  • Rymashevskij Aleksandr Nikolaevich
  • Opruzhenkov Anton Vladimirovich
RU2435515C2
METHOD OF PREDICTING SYNDROME OF INTRAUTERINE FOETAL DEVELOPMENT RETARDATION IN THIRD GESTATION TRIMESTER IN CASE OF REACTIVATION OF CHRONIC CYTOMEGALOVIRAL INFECTION IN WOMEN WITH THREAT OF MISCARRIAGE IN SECOND TRIMESTER OF PREGNANCY 2013
  • Gorikov Igor' Nikolaevich
  • Lutsenko Mikhail Timofeevich
  • Kolosov Viktor Pavlovich
  • Zabolotskikh Tat'Jana Vladimirovna
  • Grigorenko Aleksej Aleksandrovich
  • Nakhamchen Leonid Girshevich
RU2563130C2
METHOD FOR PREDICTION OF CHORIOAMNIONITIS DEVELOPMENT IN WOMEN WITH EXACERBATION OF CYTOMEGALOVIRAL INFECTION IN THE SECOND TRIMESTER OF PREGNANCY AND THREAT OF MISCARRIAGE 2020
  • Gorikov Igor Nikolaevich
  • Kolosov Viktor Pavlovich
  • Andrievskaia Irina Anatolevna
  • Milovanov Andrei Petrovich
  • Nakhamchen Leonid Girshevich
RU2733168C1
METHOD FOR PREDICTION OF ADVERSE PERINATAL OUTCOMES WITH FETAL GROWTH RETARDATION SYNDROME IN WOMEN WITH REACTIVATION OF CHRONIC CYTOMEGALOVIRUS INFECTION IN SECOND TRIMESTER OF PREGNANCY COMPLICATED BY RETROPLACENTARY HEMATOMA 2016
  • Gorikov Igor Nikolaevich
  • Kolosov Viktor Pavlovich
  • Ishutina Natalya Aleksandrovna
  • Sudakov Anatolij Georgievich
RU2648472C1
METHOD FOR SETTING EARLY STAGE CYTOMEGALOVIRUS INFECTION DIAGNOSIS IN NEWBORNS 2006
  • Kravchenko Larisa Vakhtangovna
  • Afonin Aleksandr Alekseevich
  • Afonina Tamara Andreevna
RU2317550C1
METHOD FOR PREDICTION OF NONSPECIFIC COMPLICATIONS OF ACUTE INTESTINAL INFECTIONS WITH HEMORRHAGIC COLITIS SYNDROME IN CHILDREN 2019
  • Klimova Olga Ivanovna
  • Gonchar Natalya Vasilevna
  • Skripchenko Natalya Viktorovna
  • Lobzin Yurij Vladimirovich
  • Grigorev Stepan Grigorevich
RU2704132C1
METHOD FOR PREDICTION OF MISCARRIAGE IN THE FIRST TRIMESTER AT CYTOMEGALOVIRUS INFECTION 2015
  • Andrievskaya Irina Anatolevna
  • Lutsenko Mikhail Timofeevich
RU2599516C1

RU 2 822 967 C1

Authors

Markin Ivan Vasilevich

Rogozina Nataliya Vasilevna

Vasilev Valerij Viktorovich

Goleva Olga Vladimirovna

Grigorev Stepan Grigorevich

Dates

2024-07-16Published

2023-06-30Filed