FIELD: medicine.
SUBSTANCE: invention relates to infectious diseases and can be used to predict the development of congenital cytomegalovirus infection in newborns in order to prevent unfavorable outcomes. Includes assessment of: presence of acute respiratory viral infection during pregnancy, burdened obstetric-gynecological history, threatened miscarriage of present pregnancy, disturbed uterine-placental circulation, ultrasound markers of prenatal pathology, blood PCR results with detection of CMV DNA with indication of trimester of examination. Further, the obtained data are used to determine the risk of congenital infectious diseases (LDF) by formulas: LDF1 = (X1×0.64 − X2×0.2 + X3×0.84 + X4×1.53 + X5×0.69 + X6×0.14 − X7×0.92) − 1.22; LDF2 = (X1×7.68+X2×3.64 + X3×2.72 − X4×2.5 + X5×2.95 + X6×2.21 +X7×1.31) − 8.73; if LDF2 is more than LDF1, development of congenital cytomegalovirus infection in newborns is predicted.
EFFECT: method enables to reduce the examination time and increase the accuracy of early and timely prediction of the development of congenital cytomegalovirus infection in newborns in the antenatal period, and also enables the timely prescription of etiotropic therapy in the ante- and neonatal period, by assessing the most significant clinical-anamnestic, laboratory and instrumental values.
1 cl, 3 ex
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Authors
Dates
2024-07-16—Published
2023-06-30—Filed