TRANSGENIC MOUSE USED FOR INVESTIGATION OF REPARATIVE REGENERATION OF SKIN WOUND Russian patent published in 2024 - IPC C12N5/10 A01K67/00 

Abstract RU 2823992 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the use of a transgenic mouse with inducible expression of the Xenopus laevis xAG gene with a STOP cassette and under the control of a Tet-On promoter as a model animal for studying reparative skin wound regeneration.

EFFECT: invention provides the stimulation of the regenerative abilities of the created transgenic animal (model) under the influence of endogenous expression of regeneration factors active in lower vertebrate organisms.

1 cl, 6 dwg, 2 ex

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RU 2 823 992 C1

Authors

Kosykh Anastasiia Valerevna

Zhigmitova Elena Bazyrovna

Martynova Natalia Iurevna

Tereshina Mariia Borisovna

Didych Dmitrii Aleksandrovich

Silaeva Iuliia Iurevna

Bruter Aleksandra Vladimirovna,

Zaraiskii Andrei Georgievich

Gurskaia Nadezhda Georgievna

Dates

2024-07-31Published

2023-10-30Filed