FIELD: chemistry; pharmaceutics.
SUBSTANCE: invention relates to chemistry and pharmaceutics, specifically to a compound of formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutical composition having activity of a positive allosteric modulator D1, based on it, a method of treating and/or preventing cognitively related and negative symptoms of schizophrenia, mild cognitive impairment, impulsivity, Parkinson's disease and other movement disorders, dementia with Lewy bodies, Alzheimer's disease, for which the introduction of a positive allosteric modulator D1 is indicated, and a method of treating Parkinson's disease and other movement disorders, Alzheimer's disease or cognitively related and negative symptoms of schizophrenia, for which the administration of a positive allosteric modulator D1 is indicated, which include administering a compound of formula (I) or a pharmaceutically acceptable salt thereof in an effective amount.
EFFECT: use of the invention enables effective treatment of diseases for which the introduction of a positive allosteric modulator D1 is indicated.
9 cl
Title | Year | Author | Number |
---|---|---|---|
SUBSTITUTED TETRAHYDROISOQUINOLINE DERIVATIVE AS POSITIVE ALLOSTERIC MODULATOR D1 | 2020 |
|
RU2824581C2 |
IMIDAZODIAZEPINE COMPOUND | 2016 |
|
RU2712968C2 |
TRISUBSTITUTED 1,2,4-TRIAZOLES | 2008 |
|
RU2474579C2 |
3-AZABICYCLO[3,1,0]HEXYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | 2009 |
|
RU2510396C2 |
IMIDAZODIAZEPINE COMPOUND | 2016 |
|
RU2777915C2 |
COMBINATIONS CONTAINING mGluR MODULATORS FOR TREATING PARKINSON'S DISEASE | 2009 |
|
RU2496494C2 |
1H-INDAZOLES, 1,2-BENZISOXAZOLES AND 1,2-BENZISOTHIAZOLES, SYNTHESIS THEREOF AND USE | 2004 |
|
RU2389729C2 |
ETHYNYL DERIVATIVES | 2016 |
|
RU2712633C1 |
PYRIDOPYRIMIDINONES AND USE THEREOF AS MODULATORS OF N-METHYL-D-ASPARTATE RECEPTOR | 2016 |
|
RU2717665C2 |
NEW BENZAZEPIN DERIVATIVES | 2003 |
|
RU2423353C1 |
Authors
Dates
2024-08-09—Published
2020-06-29—Filed