CELL CULTURE SYSTEMS AND METHODS Russian patent published in 2024 - IPC A61K35/14 A61K35/17 A61K35/26 A61K35/28 A61K39/00 C07K14/525 

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to a cell culture system and method. Cell culture system comprises: a first zone for a liquid reservoir containing a cell culture medium; second zone for waste tank; one or more pumps; at least first and second gas-tight cultivation chambers; a substrate for accommodating and supporting the first and second cell culture chambers simultaneously and one or more gas-permeable tubes. Cell culture method involves: providing a cell culture system; loading the liquid tank into the first zone and the waste tank into the second zone; loading a first cell culture chamber of a first size and/or shape onto a first portion of the substrate; loading a second cell culture chamber of a second size and/or shape onto a second portion of the substrate; flowing the cell culture medium into the first cell culture chamber; and transferring the supernatant from the first cell culture chamber to the second cell culture chamber.

EFFECT: group of inventions provides an improved automated technology for producing cellular immunotherapy products, thereby reducing the risk of contamination.

13 cl, 12 dwg