FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, particularly to the use of N1-hydroxy-N4-phenylbutanediamide derivatives of formula 1 as metalloproteinase inhibitors. In formula 1, R is selected from H, F, Cl, Br, I and O-CH3.
EFFECT: inhibiting action of compounds of formula 1 on metalloproteinases.
3 cl, 4 dwg, 4 tbl, 9 ex
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