FLUORESCENT CONTRASTING NEAR INFRARED AGENT AND METHOD OF FLUORESCENT TOMOGRAPHY Russian patent published in 2009 - IPC A61K49/06 

FIELD: chemistry.

SUBSTANCE: invention refers to applications of compound of formula

I or its pharmaceutically acceptable salt: where R¹, R², R⁷ and R⁸ stand for C₁-C₁₀ alkyl group, etc.; R³, R⁴, R⁵, R⁶, R⁹, R¹⁰, R¹¹ and R¹² stand for hydrogen atom, C₁-C₆ alkyl group, aryl group, etc.; X¹ and X² stand for C₁-C₁₅ alkyl group or aryl group, and X¹ and X² together contain 0 to 4 carboxyl groups; m¹, m² and m³ stand for 0 or 1; L¹~L⁷ independently stand for methine group; M stands for hydrogen, metal atom, or quaternary ammonium salt; n stands for integer 1 to 7 required to neutralise the charge, to produce fluorescent contrasting near infrared agent used in fluorescent body imaging method; actually fluorescent contrasting near infrared agent containing compound of formula I or its pharmaceutically acceptable salt.

EFFECT: use of aforesaid compound to produce contrasting agents enables to produce quickly high-detail contrast images in living organism research.

11 cl, 16 ex, 8 dwg