FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry, and concerns creating pharmaceutical radiopreparations (PRP) on the basis of peptide analogues of radioisotope-marked neuroregulatory peptides for the purpose of diagnosing malignant tumours. Substance of the invention: the pharmaceutical radiopreparations for diagnosing melanoma and its metastases containing a linear heptapeptide of formula: Ac-Nle-Asp-His-dPhe-Arg-Trp-Lys-NH2, 99mTc marked through a peptide chelating group of formula: Gly-Cys-Gly-Cys-H covalently bond with the e-amino group of C-terminal lysine.
EFFECT: invention enables fast and effective diagnosis of malignant tumours.
8 dwg, 1 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
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