FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to novel spiro-linked 3H-pyrroles - 8-amino-1-imino-6-morpholin-4-yl-2-oxa-7-azaspiro[4.4]nona-3,6,8-triene-9-carbonitriles of general formula (1) 
, where R1=R2=CH3 (1a); R1+R2=(CH2)5 (1b); R1+R2=(CH2)6 (1c); R1+R2=(CH2)10 (1d). The method involves suspension of the corresponding 4-oxoalkane-1,1,2,2-tetracarbonitrile of formula (2) , 
, R1=R2=CH3 (2a); R1+R2=(CH2)5 (2b); R1+R2=(CH2)6 (2c); R1+R2=(CH2)10 (2d) in a mixture of water and propanol-2 in ratio of 10:1, followed by addition of morpholine in molar ratio of 1:2.
EFFECT: high efficiency of the method.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING 5-AMINO-3H-PYRROLE-4-CARBONONITRILES DERIVATIVES | 2018 |
|
RU2675600C1 |
| METHOD OF PRODUCING 3-AMINO-8-HYDROXY-1,6-DIOXO-2,7-DIAZASPIRO[4,4]NON-3-ENE-4-CARBONITRILES | 2012 |
|
RU2495040C1 |
| METHOD FOR PRODUCING 4-OXOALKANE-1,1,2,2-TETRACARBONITRILES | 2015 |
|
RU2577537C1 |
| 1-IMINO-2,3,4,5-TETRAHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-3,4-DIONES | 2016 |
|
RU2613967C1 |
| METHOD OF OBTAINING 2-OXO-4-CYANO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDES | 2011 |
|
RU2475480C1 |
| METHOD FOR PREPARING 6-IMINO-2,7-DIOXABICYCLO[3,2,1]OCTANE-4,4,5-TRICARBONITRILES | 2014 |
|
RU2545459C1 |
| METHOD FOR PREPARING AMMONIUM SALTS OF 3-AMINO-8-HYDROXY-1,6-DIOXO-4-CYANO-2,7-DIAASPIRO [4,4] NON-3-EN-2-IDS | 2016 |
|
RU2631856C1 |
| METHOD OF THE PREPARATION OF PYRROLO[3,4-C]QUINOLINES | 2022 |
|
RU2802332C1 |
| PROCESS OF OBTAINING METHYL ESTER 2-HALO-6-ALKYL-3-CYANOSUNICOTIN ACIDS | 2016 |
|
RU2616980C1 |
| ETHYL 1,6-DIARYL-4-AROYL-3-HYDROXY-2-OXO-8-PHENYL-1,7-DIAZASPIRO[4,4]NONA-3,6,8-TRIEN-9-CARBOXILATES AND METHOD OF THEIR OBTAINING | 2011 |
|
RU2467010C1 |
