METHOD FOR PRODUCING 4-OXOALKANE-1,1,2,2-TETRACARBONITRILES Russian patent published in 2016 - IPC C07C253/30 C07C255/17 C07C255/31 C07C255/40 C07D333/24 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 4-oxoalkane-1,1,2,2-tetracarbonitriles of general formula (A), which can be used as starting compounds for synthesis of different heterocyclic structures. In general formula (A) R¹=R²=Me, R³= H (A1); R¹= , R²=R³=H (A2); R₁+R₂=, R₃=H (A3); R¹+R²=(CH₂)₅, R³=H (A4); R¹+R²=(CH₂)₆, R³=H (A5); R¹=Ph, R²=Me, R³=H (A6); R¹=4-Cl-C₆H₄, R²=Me, R³=H (A7); R¹=4-MeOC₆H₄, R²=Me, R³=H (A8); R¹=R²=Ph, R³=H (A9); R¹=, R²=R³=H (A10). Proposed method comprises heating mixture of tetracyanoethylene and corresponding ketone in equimolar amounts. Method is as follows: mixture is further added with p-toluene sulphonic acid while heating at temperature of 50-60°C until complete dissolution of tetracyanoethylene in obtained melt of p-toluene sulphonic acid and ketone with subsequent crystallisation of target product.

EFFECT: method enables reaction without solvent, as well as reduce process duration.

1 cl, 10 ex