DIAGNOSTIC TECHNIQUE FOR MICROANGIOPATHY IN DIABETIC PATIENTS Russian patent published in 2015 - IPC A61B5/26 A61B5/83 

FIELD: medicine.

SUBSTANCE: rest capillaroscopy is followed by measuring changes in the capillary state structure. That is accompanied by acapillaroscopy and oxygenometry with four provocative tests involving the examined limb exposure to physical factors, including a cuff occlusion, a cold test, a thermal test, and a test with arms lifted up. Each test is followed by measuring an oxygen saturation index (SaO₂) and a capillaroscopy values reset time (t). After the cuff occlusion SaO_2occl. and t_occl.are supposed to be measured. The cold test is followed by measuring SaO_2cold and t_cold. The thermal test - by measuring SaO_2therm. and t_therm.. SaO_{2lift up} and t_{lift up} appear after the test with arms lifted up has been completed. If SaO_2occl. - 85-90%, t_occl. <20 seconds, SaO_2cold >95%, t_cold <5 minutes, SaO_2therm. >95%, t_therm. <4 minutes 30 seconds, SaO_{2lift up} - 85-90%, t_{lift up} <15 seconds, early microangiopathy is diagnosed. If SaO_2occl. - 80-85%, t_occl. - 20-30 seconds, SaO_2cold - 87-95%, t_cold - 5 minutes - 6 minutes 30 seconds; SaO_2therm. - 90-95%, t_therm. <4 minutes 30 seconds - 5 minutes, SaO_{2lift up} - 78-85%, t_{lift up} - 15-25 seconds, moderate microangiopathy is diagnosed. SaO_2occl.<80%, t_occl.>30 seconds; SaO_2cold <87%, t_cold >6 minutes 30 seconds; SaO_2therm. <90%, t_therm. >5 min; SaO_{2lift up} <78%, t_{lift up}> 25 seconds show pronounced microangiopathy.

EFFECT: method provides diagnosing microangiopathy as accurately as possible in the given category of patients by the early integrated microvasculature assessment associated with detecting the capillary reserve level.

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