FIELD: chemistry.
SUBSTANCE: invention refers to a method for producing 4-(1-adamantyl)aniline, which is a starter compound for producing adamantane derivatives exhibiting various types of biological activity, as well as representing monomers in a process of synthesis of polymers with improved performance. The method consists in carrying out a reaction of 1-adamantol and acetanilide at 80°C for 3 hours in a trifluoroacetic acid medium taken as a solvent in molar ratio of 1-adamantol : acetanilide : trifluoroacetic acid = 1:1.2÷1.4:4÷8. A protective group is separated in the prepared product and neutralised with an alkali solution.
EFFECT: method enables performing the process selectively and preparing the product with 96% yield and containing 99,4% of the basic compound.
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| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING 4-(1-ADAMANTYL)ANILINE | 2014 |
|
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