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IPC

A61N5/67(2006-01-01)

A61K31/409(2006-01-01)

A61K47/22(2006-01-01)

A61P35/00(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2020108110, 2020-02-25

(24)

Start date

2020-02-25

(22)

Actual filing date

2020-02-25

(45)

Published

2020-06-25

(72)

Inventor

Abramova Olga BorisovnaDrozhzhina Valentina VladimirovnaChurikova Tatyana PetrovnaBeregovskaya Ekaterina AleksandrovnaKaprin Andrej Dmitrievich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Radiologii" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Radiologii" Minzdrava Rossii)

METHOD OF PHOTODYNAMIC THERAPY OF TRANSPLANTED ECTODERMAL TUMOR OF MELANOMA B16 OF MICE Russian patent published in 2020 - IPC A61N5/67 A61K31/409 A61K47/22 A61P35/00 G09B23/28

Abstract RU 2724867 C2

FIELD: medicine.

SUBSTANCE: invention relates to experimental medicine and can be used for photodynamic therapy of transplanted ectodermal tumor of melanoma B16 of mice. Photosensitiser (PS) of Fotoran E6 is administered in dose of 5 mg/kg. Wave length is in range of 660–670 nm. Laser therapy is carried out with the following parameters: Ps=0,25 W/cm², E=152 J/cm². If administered intravenously, the time between administration and irradiation session is 45 minutes to 1 hour, while intraperitoneal exposure makes 1.5 to 2 hours.

EFFECT: method provides complete tumor eradication with minimal damage of surrounding healthy tissues due to optimal time from the moment of administering PS to irradiation with laser.

1 cl, 2 tbl

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RU 2 724 867 C2

Authors

Abramova Olga Borisovna

Drozhzhina Valentina Vladimirovna

Churikova Tatyana Petrovna

Beregovskaya Ekaterina Aleksandrovna

Kaprin Andrej Dmitrievich

Dates

2020-06-25—Published

2020-02-25—Filed