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(19)

RU

(11)

2 774 589

(13)

C1

(51)

IPC

A61B18/20(2006-01-01)

A61N5/67(2006-01-01)

A61K31/409(2006-01-01)

A61K47/36(2006-01-01)

A61P35/00(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2021131845, 2021-10-30

(24)

Start date

2021-10-30

(22)

Actual filing date

2021-10-30

(45)

Published

2022-06-21

(72)

Inventor

Abramova Olga BorisovnaKozlovtseva Ekaterina AleksandrovnaChurikova Tatiana PetrovnaDrozhzhina Valentina VladimirovnaArkhipova Liubov MikhailovnaIvanov Sergei AnatolevichKaprin Andrei Dmitrievich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Radiologii» Ministerstva Zdravookhraneniia Rossiiskoi Federatsii Radiologii» Minzdrava Rossii)

METHOD FOR CARRYING OUT PHOTODYNAMIC THERAPY OF SOLID EHRLICH CARCINOMA IN MICE Russian patent published in 2022 - IPC A61B18/20 A61N5/67 A61K31/409 A61K47/36 A61P35/00 G09B23/28 

Abstract RU 2774589 C1

FIELD: experimental medicine.

SUBSTANCE: invention relates to experimental medicine and can be used for photodynamic therapy of grafted Ehrlich solid carcinoma in mice. To do this, the photosensitizer Heliochlorin is administered intravenously at a dose of 5 mg/kg. Then the tumor is irradiated with laser radiation E=150 J/cm2 with a wavelength of 662 nm, power density Ps=0.48 W/cm2, drug-light interval is 45 minutes.

EFFECT: invention provides the maximum antitumor effect in this category of laboratory animals on the 90th day after the photodynamic therapy.

1 cl, 3 tbl

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RU 2 774 589 C1

Authors

Abramova Olga Borisovna

Kozlovtseva Ekaterina Aleksandrovna

Churikova Tatiana Petrovna

Drozhzhina Valentina Vladimirovna

Arkhipova Liubov Mikhailovna

Ivanov Sergei Anatolevich

Kaprin Andrei Dmitrievich

Dates

2022-06-21—Published

2021-10-30—Filed

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