METHOD FOR COMBINED TREATMENT OF LOCALIZED T-TNMLARYNX CANCER Russian patent published in 2021 - IPC A61B18/20 A61K31/409 A61K33/14 A61P35/00 

Abstract RU 2759743 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to oncology, and can be used in the combined treatment of localized (T1-T2N0M0) laryngeal cancer. The method includes removal of the larynx tumor and intraoperative photodynamic therapy on the bed of the removed tumor. 3 hours before the operation, intravenous drip injection of the chlorin series photosensitizer Photolon is performed in a single dose of 1 mg/kg of body weight with preliminary dilution in 0.9% sterile isotonic sodium chloride solution 100 ml. Next, the surgical stage of closed endolaryngeal resection of the larynx or open resection of the larynx is performed, after which photodynamic therapy is performed intraoperatively on the bed of the removed neoplasm.

EFFECT: use of the invention makes it possible to improve the long-term results of treatment by increasing ablasticity without increasing the number of intraoperative and early postoperative complications, and ensures the prevention of local recurrence and dissemination of the tumor.

1 cl, 6 dwg, 2 ex

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RU 2 759 743 C2

Authors

Sevriukov Feliks Evgenevich

Baryshev Vladimir Viktorovich

Rozhnov Vitalii Anatolevich

Pankratov Vladimir Aleksandrovich

Akki Ernest Diliaverovich

Spirin Pavel Igorevich

Panaseikin Iurii Aleksandrovich

Kapinus Viktoriia Nikolaevna

Spichenkova Irina Sergeevna

Iaroslavtseva-Isaeva Elena Viktorovna

Polkin Viacheslav Viktorovich

Kaplan Mikhail Aleksandrovich,

Kaprin Andrei Dmitrievich

Dates

2021-11-17Published

2021-04-14Filed