FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to oncology, and can be used in the combined treatment of localized (T1-T2N0M0) laryngeal cancer. The method includes removal of the larynx tumor and intraoperative photodynamic therapy on the bed of the removed tumor. 3 hours before the operation, intravenous drip injection of the chlorin series photosensitizer Photolon is performed in a single dose of 1 mg/kg of body weight with preliminary dilution in 0.9% sterile isotonic sodium chloride solution 100 ml. Next, the surgical stage of closed endolaryngeal resection of the larynx or open resection of the larynx is performed, after which photodynamic therapy is performed intraoperatively on the bed of the removed neoplasm.
EFFECT: use of the invention makes it possible to improve the long-term results of treatment by increasing ablasticity without increasing the number of intraoperative and early postoperative complications, and ensures the prevention of local recurrence and dissemination of the tumor.
1 cl, 6 dwg, 2 ex
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Authors
Dates
2021-11-17—Published
2021-04-14—Filed