RODENTS HAVING CONSTRUCTED SECTION OF HEAVY CHAIN DIVERSITY Russian patent published in 2021 - IPC A01K67/27 C07K14/435 C07K14/715 C07K16/00

Abstract RU 2763320 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to a rat or a mouse containing an embryonic cell that contains an ungrouped variable section of an immunoglobulin heavy chain functionally bound with an endogenous constant section of the immunoglobulin heavy chain, and B-cell, a method for its production, as well as to its cell, tissue or embryo.

EFFECT: invention is effective for the production of an antibody.

65 cl, 21 dwg, 12 tbl, 8 ex

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RU 2 763 320 C2

Authors

Macdonald, Lynn

Mcwhirter, John

Murphy, Andrew, J.

Dates

2021-12-28—Published

2017-01-12—Filed